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Cetirizine selectively inhibits histamine H1 receptor sites in blood vessels, GI tract, and respiratory tract, which in turn inhibits physiologic effects that histamine normally induces at H1 receptor sites. Bedtime dosing may be useful if sedation is a problem.Pseudoephedrine stimulates vasoconstriction by directly activating alpha-adrenergic receptors of the respiratory mucosa.Selective leukotriene receptor antagonist that inhibits the cysteinyl leukotriene (Cys LT 1) receptor.Selectively prevents action of leukotrienes released by mast cells and eosinophils.
Major metabolite of loratadine, which after ingestion is extensively metabolized to active metabolite 3-hydroxydesloratadine.
They can be used prn, but adverse effects may limit their usefulness when taken on a daily basis.
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